Preferred Label : Filgrastim-sndz;
Obsolete resource : true;
NCIt synonyms : Filgrastim Biosimilar Filgrastim-sndz;
NCIt definition : A biosimilar of filgrastim, a recombinant form of the endogenous cytokine human granulocyte
colony-stimulating factor (G-CSF), with hematopoietic activity. Filgrastim-sndz specifically
binds to and activates G-CSF receptors with the same biological activity and stability
as the endogenous cytokine, thereby controlling the production, differentiation, and
function of neutrophilic granulocyte progenitors. This may decrease the duration and
prevent the incidence of chemotherapy-induced neutropenia (CIN).;
NCIt note : See 'Filgrastim(C1474)';
Concept status : Retired_Concept;
Drug name : Zarxio;
NCI Metathesaurus CUI : CL524901;
Origin ID : C137804;
UMLS CUI : C3892863;
Automatic exact mappings (from CISMeF team)
Semantic type(s)