Preferred Label : Tbo-filgrastim;
Obsolete resource : true;
NCIt synonyms : Filgrastim Biosimilar Tbo-filgrastim; Filgrastim XM02;
NCIt definition : A recombinant form of the endogenous cytokine human granulocyte colony-stimulating
factor (G-CSF), with hematopoietic activity. Upon administration, tbo-filgrastim specifically
binds to and activates G-CSF receptors, thereby controlling the production, differentiation,
and function of neutrophilic granulocyte progenitors. This stimulates the proliferation
of neutrophils and may decrease the duration and prevent the incidence of chemotherapy-induced
neutropenia (CIN). The pharmacokinetic and pharmacodynamic profile of tbo-filgrastim
is bioequivalent to filgrastim.;
NCIt note : See 'Filgrastim(C1474)';
Concept status : Retired_Concept;
Drug name : Granix;
Molecule name : XM02;
NCI Metathesaurus CUI : CL524902;
Origin ID : C137803;
UMLS CUI : C3542463;
Automatic exact mappings (from CISMeF team)
- Semantic type(s)
