Preferred Label : Hematoporphyrin Derivative;
Obsolete resource : true;
NCIt synonyms : HPD;
NCIt related terms : photofrin;
NCIt definition : A complex mixture of monomeric and aggregated porphyrins with photosensitizing activity.
Upon systemic administration, hematoporphyrin derivatives accumulate in tumor cells
and, once activated by red laser light (630 nm), in the presence of oxygen, produce
singlet oxygen and other reactive oxygen radicals, resulting in local radical-mediated
tumor cell death.;
Alternative definition : NCI-GLOSS: A drug used in photodynamic therapy that is absorbed by tumor cells. When
exposed to light, it becomes active and kills the cancer cells.;
NCIt note : See 'Porfimer Sodium(C1071)';
Concept status : Retired_Concept;
CAS number : 68335-15-9; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 68335-15-9
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G-SRS /a ;
Drug name : Photofrin;
NSC code : 265328;
Codes from synonyms : CDR0000046105; NSC0603062; CDR0000045322;
Origin ID : C1377;
UMLS CUI : C0121300;
Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
