Preferred Label : Pathologic Stage III Cutaneous Melanoma AJCC v8;
NCIt synonyms : Pathologic Stage III Melanoma of the Skin AJCC v8;
NCIt related terms : Stage III Cutaneous (Skin) Melanoma;
NCIt definition : Stage III includes: IIIA: (T1a/b-T2a, N1a or N2a, M0); IIIB: (T0, N1b, N1c, M0); (T1a/b-T2a,
N1b/c or N2b, M0); (T2b/T3a, N1a-N2b, M0); IIIC: (T0, N2b, N2c, N3b or N3c); (T1a-T3a,
N2c or N3a/b/c, M0); (T3b/T4a, Any N greater than or equal to N1, M0); (T4b, N1a-N2c,
M0); IIID: (T4b, N3a/b/c, M0). T1a: Tumor measuring less than 0.8 mm in thickness.
Ulceration status: Without ulceration. T1b: Tumor measuring less than 0.8 mm in thickness
with ulceration, or 0.8-1.0 mm with or without ulceration. T2a: Tumor measuring more
than 1.0 and equal to or less than 2.0 mm in thickness. Ulceration status: Without
ulceration. T0: No evidence of primary tumor (e.g., unknown primary or completely
regressed melanoma). Thickness: Not applicable. Ulceration status: Not applicable.
T2b: Tumor measuring more than 1.0 and equal to or less than 2.0 mm in thickness.
Ulceration status: With ulceration. T3a: Tumor measuring more than 2.0 and equal to
or less than 4.0 mm in thickness. Ulceration status: Without ulceration. T3b: Tumor
measuring more than 2.0 and equal to or less than 4.0 mm in thickness. Ulceration
status: With ulceration. T4a: Tumor measuring more than 4.0 mm in thickness. Ulceration
status: Without ulceration. T4b: Tumor measuring more than 4.0 mm in thickness. Ulceration
status: With ulceration. N1a: One clinically occult nodal metastasis (i.e., detected
by sentinel lymph node biopsy). Presence of in-transit, satellite, and/or microsatellite
metastases: No. N2a: Two or three clinically occult nodal metastases (i.e., detected
by sentinel lymph node biopsy). Presence of in-transit, satellite, and/or microsatellite
metastases: No. N1b: One clinically detected nodal metastasis. Presence of in-transit,
satellite, and/or microsatellite metastases: No. N1c: No regional lymph node disease.
Presence of in-transit, satellite, and/or microsatellite metastases: Yes. N2b: Two
or three nodal metastases at least one of which was clinically detected. Presence
of in-transit, satellite, and/or microsatellite metastases: No. N2c: One clinically
occult nodal metastasis. Presence of in-transit, satellite, and/or microsatellite
metastases: Yes. N3b: Four or more nodal metastases, at least one of which was clinically
detected, or presence of any number of matted nodes. Presence of in-transit, satellite,
and/or microsatellite metastases: No. N3c: Two or more clinically occult nodal metastases.
Presence of in-transit, satellite, and/or microsatellite metastases: Yes. N3a: Four
or more clinically occult nodal metastasis (i.e., detected by sentinel lymph node
biopsy). Presence of in-transit, satellite, and/or microsatellite metastases: No.
M0: No evidence of distant metastasis. LDH level is not applicable. (AJCC 8th ed.);
Neoplastic status : Malignant;
NCI Metathesaurus CUI : CL524851;
Origin ID : C137670;
UMLS CUI : C4527184;
Disease may have findings
- Has associated anatomic sites
- Semantic type(s)
- concept_is_in_subset
- disease_excludes_finding
- disease_has_abnormal_cell
- disease_has_finding
- disease_has_normal_cell_origin
- disease_has_normal_tissue_origin
- disease_has_primary_anatomic_site
- disease_is_stage
