G-Quartets - CISMeF

Preferred Label : G-Quartets;

NCIt synonyms : G-Quadruplexes DNA; G-Quartet Structures; G-Quadruplexes; G4-DNA; G-Tetrads; G-Quadruplex;

NCIt definition : G-quadruplexes are multi-stranded structures held together by square planes of four guanines ('G-quartets') interacting by forming Hoogsteen hydrogen bonds. G-quartet structures has been developed as novel anti-HIV agents. Several critical structure-activity relationships between HIV-1 integrase and G-quartet oligonucleotides have been demonstrated.;

Details

Origin ID

C13725;

UMLS CUI

C1517336;

Currated CISMeF NLP mapping
- G-Quadruplexes [MeSH Descriptor]
- G-Quadruplexes [MeSH concept]
- G-Quadruplexes, DNA [MeSH concept]
Semantic type(s)
- Nucleotide Sequence [UMLS semantic type]
UMLS correspondences (same concept)
- G-Quadruplexes [MeSH concept]
- G-Quadruplexes [MeSH Descriptor]

Keyword's position in hierarchy(ies) :

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