Fostriecin - CISMeF

Preferred Label : Fostriecin;

NCIt synonyms : 2H-pyran-2-one,5,6-dihydro-6-(3,6,13-trihydroxy-3-methyl-4-(phosphonooxy)-1,7,9,11,-tridecatetraenyl)-,trans; FST;

NCIt related terms : Phosphotrienin;

NCIt definition : An anti-tumor antibiotic isolated from the bacterium Streptomyces pulveraceus. Fostriecin inhibits topoisomerase II catalytic activity, resulting in impaired DNA and RNA synthesis in various malignant cell types. This agent also inhibits serine/threonine protein phosphatase type 2A in some tumor cell types, thereby interfering with cellular proliferation and differentiation. (NCI04);

UNII : ZO1648L551;

InChIKey : ZMQRJWIYMXZORG-DSWNLJKISA-N;

CAS number : 87810-56-8;

Chemical formula : C19H27O9P;

NSC code : 339638;

Codes from synonyms : NSC0339638;

Détails

Origin ID

C1372;

UMLS CUI

C0118175;

Automatic exact mappings (from CISMeF team)
- Follistatin [OMIM gene]
Currated CISMeF NLP mapping
- fostriecin [MeSH concept]
- fostriecin [MeSH Supplementary Concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- fostriecin [MeSH concept]
- fostriecin [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_salt_form
- Fostriecin Sodium [NCIt concept]
is_free_acid_or_base_form_of
- Fostriecin Sodium [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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