Preferred Label : Fostriecin;
NCIt synonyms : 2H-pyran-2-one,5,6-dihydro-6-(3,6,13-trihydroxy-3-methyl-4-(phosphonooxy)-1,7,9,11,-tridecatetraenyl)-,trans; FST;
NCIt related terms : Phosphotrienin;
NCIt definition : An anti-tumor antibiotic isolated from the bacterium Streptomyces pulveraceus. Fostriecin
inhibits topoisomerase II catalytic activity, resulting in impaired DNA and RNA synthesis
in various malignant cell types. This agent also inhibits serine/threonine protein
phosphatase type 2A in some tumor cell types, thereby interfering with cellular proliferation
and differentiation. (NCI04);
UNII : ZO1648L551;
InChIKey : ZMQRJWIYMXZORG-DSWNLJKISA-N;
CAS number : 87810-56-8;
Chemical formula : C19H27O9P;
NSC code : 339638;
Codes from synonyms : NSC0339638;
Origin ID : C1372;
UMLS CUI : C0118175;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
