Internal Ribosome Entry Site

Preferred Label : Internal Ribosome Entry Site;

NCIt synonyms : Ribosome Entry Site; IRES;

NCIt definition : Internal ribosome entry site (IRES) is a translational cis-acting element that directs ribosomes to the start codon by a cap-independent mechanism. IRESs are usually about 450 nucleotides in length and were first identified in picornavirus RNAs. IRESs can fold into a stable secondary hairpin structure to be incompatible with efficient translation by ribosomal scanning. (NCI);

Details

Origin ID

C13716;

UMLS CUI

C1512886;

Anatomic structure is physical part of
- Cell [NCIt concept]
- Chromosome [NCIt concept]
Automatic exact mappings (from CISMeF team)
- Internal Ribosome Entry Sites [MeSH concept]
Currated CISMeF NLP mapping
- Internal Ribosome Entry Sites [MeSH Descriptor]
Semantic type(s)
- Nucleotide Sequence [UMLS semantic type]
UMLS correspondences (same concept)
- Internal Ribosome Entry Sites [MeSH Descriptor]

Keyword's position in hierarchy(ies) :

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