Preferred Label : N-acetylcysteine/Simethicone Solution;
NCIt definition : An oral solution composed of N-acetylcysteine, a synthetic N-acetyl derivative of
the endogenous amino acid L-cysteine, and simethicone, a mixture of polydimethylsiloxanes
and hydrated silica gel, with mucolytic and antifoaming activities. Upon oral administration
of the mucolytic solution, N-acetylcysteine breaks down disulfide bonds in mucoproteins,
resulting in liquification of mucus in the upper respiratory tract. Simethicone reduces
the surface tension of gas bubbles causing them to coalesce into larger bubbles that
can be passed more easily. This increases the passage of mucus and gas bubbles from
the upper digestive tract. This may also increase visibility of the gastric mucosa
during upper endoscopy.;
NCI Metathesaurus CUI : CL524750;
Origin ID : C136988;
UMLS CUI : C4527159;
Semantic type(s)
- concept_is_in_subset
