Clinical Stage IV Cutaneous Merkel Cell Carcinoma AJCC v8

Preferred Label : Clinical Stage IV Cutaneous Merkel Cell Carcinoma AJCC v8;

NCIt synonyms : Clinical Stage IV Neuroendocrine Carcinoma of the Skin AJCC v8;

NCIt definition : Stage IV includes: T0-4, Any N, M1. T0: No evidence of primary tumor. T1: Maximum clinical tumor diameter equal to or less than 2 cm. T2: Maximum clinical tumor diameter more than 2 cm but equal to or less than 5 cm. T3: Maximum clinical tumor diameter more than 5 cm. T4: Primary tumor invades fascia, muscle, cartilage, or bone. M1: Distant metastasis detected on clinical and/or radiologic examination. (AJCC 8th ed.);

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL524736;

Details

Origin ID

C136878;

UMLS CUI

C4527063;

Disease excludes abnormal cell
- Large Osteoclastic Giant Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Endothelial Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Disease excludes normal cell origin
- Endothelial Cell [NCIt concept]
Disease may have findings
- Diffuse Pattern [NCIt concept]
- Merkel Cell Polyoma Virus Positive [NCIt concept]
- Nodular Pattern [NCIt concept]
- Trabecular Pattern [NCIt concept]
Excludes anatomical site(s)
- Head and Neck [NCIt concept]
- Lung [NCIt concept]
Has associated anatomic sites
- Endocrine Gland [NCIt concept]
- Endocrine System [NCIt concept]
- Integumentary System [NCIt concept]
- Skin [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Favorable Clinical Outcome [NCIt concept]
- Intermediate Grade Neuroendocrine Lesion [NCIt concept]
- Well Differentiated Neuroendocrine Lesion [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Endocrine Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Malignant Neuroendocrine Cell [NCIt concept]
- Malignant Neuroendocrine Small Round Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Neuroendocrine Cell [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Clinical TNM Finding [NCIt concept]
- Cutaneous Involvement [NCIt concept]
- Cytoplasmic Membrane-Bound Granules Present [NCIt concept]
- Endocrine Differentiation [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Expression of Neuroendocrine Markers Present [NCIt concept]
- High Mitotic Activity [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Neuroendocrine Differentiation [NCIt concept]
- Poorly Differentiated Neuroendocrine Lesion [NCIt concept]
- Single Cell Necrosis [NCIt concept]
- Trabecular Pattern [NCIt concept]
disease_has_normal_cell_origin
- Endocrine Cell [NCIt concept]
- Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Dermis [NCIt concept]
- Endocrine Gland [NCIt concept]
- Endocrine System [NCIt concept]
- Skin [NCIt concept]
disease_is_stage
- AJCC v8 Stage [NCIt concept]
- Stage IV [NCIt concept]
disease_may_have_associated_disease
- Merkel Cell Polyoma Virus Infection [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Trisomy 6 [NCIt concept]
- del(1p36) [NCIt concept]

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