Spitz Melanocytoma

Preferred Label : Spitz Melanocytoma;

NCIt synonyms : Atypical Spitz Tumor; Pagetoid Spitz Nevus; Melanocytic Tumor of Unknown Malignant Potential; STUMP; Atypical Spitz Nevus; Atypical Spitz Tumor of Uncertain Malignant Potential; Spitzoid Tumor of Uncertain Malignant Potential; Spitz Tumor with One or More Atypical Features; AST;

NCIt definition : A junctional or compound melanocytic neoplasm not fulfilling the histopathologic criteria of melanoma but with one of the following features: asymmetry, predominance of single melanocytes over nests in lesions 4 mm or larger, ulceration, large dermal sheets of melanocytes, lack of maturation in dermis, deep dermal mitotic figures, extensive involvement of subcutis, and nuclear pleomorphism. (Mod Pathol 2006;19: S21);

Neoplastic status : Undetermined;

NCI Metathesaurus CUI : CL524657;

Details

Origin ID

C136825;

UMLS CUI

C4522245;

Automatic exact mappings (from CISMeF team)
- Amputation stump (body structure) [SNOMED CT concept]
- Spitzoid tumour of uncertain malignant potential [ICD-11 Subcategory]
- spitzoid melanoma [DO Concept]
CISMeF manual mappings
- atypical Spitz nevus [Disease (Nov.)]
DO Cross reference
- spitzoid melanoma [DO Concept]
Disease may have findings
- HMB-45-Positive Neoplastic Cells Present [NCIt concept]
- MAPK Pathway Activated [NCIt concept]
- S-100-Positive Neoplastic Cells Present [NCIt concept]
Has associated anatomic sites
- Integumentary System [NCIt concept]
- Skin [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- atypical Spitz nevus [Disease (Nov.)]
disease_has_abnormal_cell
- Neoplastic Cell [NCIt concept]
- Neoplastic Melanocyte [NCIt concept]
disease_has_finding
- Atypia [NCIt concept]
- Borderline Lesion [NCIt concept]
- Cutaneous Involvement [NCIt concept]
- Darkly Pigmented Melanophages Present [NCIt concept]
disease_has_normal_cell_origin
- Melanocyte [NCIt concept]
disease_has_normal_tissue_origin
- Skin Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Skin [NCIt concept]

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