" /> Lung Squamous Cell Carcinoma In Situ - CISMeF





Preferred Label : Lung Squamous Cell Carcinoma In Situ;

NCIt synonyms : Squamous Cell Lung Carcinoma In Situ; LUSC-CIS;

NCIt definition : A preinvasive bronchial neoplastic lesion affecting the squamous epithelium. It is characterized by the absence of progression of maturation from base to luminal surface, basilar zone expansion with cellular crowding throughout the epithelium, absence of the intermediate zone, and surface flattening confined to the most superficial cells. The nuclear-to-cytoplasmic ratio is often high and variable, the chromatin is coarse and uneven, and mitotic figures are present through full thickness. The cell size may be markedly increased. Anisocytosis and pleomorphism may be present. (Adapted from WHO, 2015);

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL554696;

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29/04/2024


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