Pritelivir - CISMeF

Preferred Label : Pritelivir;

NCIt synonyms : Benzeneacetamide, N-(5-(Aminosulfonyl)-4-methyl-2-thiazolyl)-N-methyl-4-(2-pyridinyl)-; N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2-(4-pyridin-2-ylphenyl)acetamide; N-(5-(Aminiosulfonyl)-4-methyl-1,3-thiazol-2-yl)-N-methyl-2-(4-(2-pyridinyl)phenyl)acetamide;

NCIt definition : A thiazolylamide and helicase-primase enzyme inhibitor that is active against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2). Pritelivir inhibits the helicase-primase complex and prevents helicase or primase catalytic cycling of viral DNA, which interferes with DNA replication and growth. This agent does not require activation by HSV thymidine kinase and has a longer plasma half-life than nucleoside analogues.;

UNII : 07HQ1TJ4JE;

InChIKey : IVZKZONQVYTCKC-UHFFFAOYSA-N;

CAS number : 348086-71-5; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 348086-71-5 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : BAY 57-1293; AIC-316;

Chemical formula : C18H18N4O3S2;

Details

Origin ID

C136516;

UMLS CUI

C3713852;

Currated CISMeF NLP mapping
- pritelivir [MeSH Supplementary Concept]
- pritelivir [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- pritelivir [MeSH concept]
- pritelivir [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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