Preferred Label : Stage III Pleural Malignant Mesothelioma AJCC v8;
NCIt related terms : Stage III Pleural Malignant Mesothelioma;
NCIt definition : Stage III includes: IIIA: (T3, N1, M0); IIIB: (T1-3, N2, M0); (T4, Any N, M0). T1:
Tumor limited to the ipsilateral parietal with or without involvement of visceral
pleura, mediastinal pleura, and diaphragmatic pleura. T2: Tumor involving each of
the ipsilateral pleural surfaces (parietal, mediastinal, diaphragmatic, and visceral
pleura) with at least one of the following features: involvement of diaphragmatic
muscle and/or extension of tumor from visceral pleura into the underlying pulmonary
parenchyma. T3: Tumor is locally advanced but potentially resectable. The tumor involves
all the ipsilateral pleural surfaces (parietal, mediastinal, diaphragmatic, and visceral
pleura) with at least one of the following features: involvement of the endothoracic
fascia, extension into the mediastinal fat, solitary, completely resectable focus
of tumor extending into the soft tissues of the chest wall, and/or nontransmural involvement
of the pericardium. T4: Tumor is locally advanced and technically unresectable. The
tumor involves all the ipsilateral pleural surfaces (parietal, mediastinal, diaphragmatic,
and visceral pleura) with at least one of the following features: diffuse extension
or multifocal masses of tumor in the chest wall, with or without associated rib destruction,
direct transdiaphragmatic extension of tumor to the peritoneum, direct extension of
tumor to the contralateral pleura, direct extension of tumor to mediastinal organs,
direct extension of tumor into the spine, and/or tumor extending through to the internal
surface of the pericardium with or without a pericardial effusion; or tumor involving
the myocardium. N1: Metastases in the ipsilateral bronchopulmonary, hilar, or mediastinal
(including the internal mammary, peridiaphragmatic, pericardial fat pad, or intercostal)
lymph nodes. N2: Metastases in the contralateral mediastinal, ipsilateral, or contralateral
supraclavicular lymph nodes. M0: No distant metastasis. (AJCC 8th ed.);
Neoplastic status : Malignant;
NCI Metathesaurus CUI : CL523709;
Origin ID : C136403;
UMLS CUI : C4521610;
Disease may have findings
- Excludes anatomical site(s)
- Has associated anatomic sites
- Semantic type(s)
- concept_is_in_subset
- disease_excludes_finding
- disease_has_abnormal_cell
- disease_has_finding
- disease_has_normal_cell_origin
- disease_has_normal_tissue_origin
- disease_has_primary_anatomic_site
- disease_is_stage
- disease_may_have_cytogenetic_abnormality
- disease_may_have_molecular_abnormality
