NCIt related terms : Cyclopentenylcytosine; 2(1H)-Pyrimidinone, 4-amino-1-[4, 5-dihydroxy- 3-(hydroxymethyl)-2-cyclopenten-1-yl]-;
NCIt definition : A pro-drug carbocyclic analogue of cytidine with antineoplastic and antiviral activities.
Cyclopentenyl cytosine (CPEC) is converted to the active metabolite cyclopentenyl
cytosine 5'-triphosphate (CPEC-TP); CPEC-TP competitively inhibits cytidine triphosphate
(CTP) synthase, thereby depleting intracellular cytidine pools and inhibiting DNA
and RNA synthesis. This agent may also induce differentiation of some tumor cell types.
The antiviral activity of this agent is broad-spectrum.;
UNII : 69MO0NDN8K;
CAS number : 90597-22-1; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 90597-22-1
alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo
G-SRS /a ;