Azimexon - CISMeF

Preferred Label : Azimexon;

NCIt synonyms : Azimexone; 2-Cyanaziridinyl-2-carbamoyl-aziridinyl-1-propane; 2-Aziridinecarboxamide, 1-[1-(2-cyano-1-aziridinyl)-1-methylethyl]; AZ;

NCIt definition : Azimexon (2-cyanaziridinyl-2-carbamoyl-aziridinyl-1-propane) is a derivative of 2-cyanaziridine. Immunostimulant which shows therapeutic effects in tumor models and experimental infections in vitro, enhancing T lymphocyte transformation and phagocytosis. The mode of action of azimexon is unknown. It has been suggested that azimexon may alkylate DNA. In cancer patients it increases leukocytosis, blood active T rosettes, T4/T8 ratio, and is used as an adjuvant to chemotherapy in the treatment of melanoma and myeloma.;

UNII : 4NJ842U6BZ;

InChIKey : RPZOFMHRRHHDPZ-UHFFFAOYSA-N;

CAS number : 64118-86-1;

Molecule name : BM 12.531; BM12531;

Chemical formula : C9H14N4O;

Details

Origin ID

C1347;

UMLS CUI

C0104835;

Currated CISMeF NLP mapping
- azimexon [Substance BNPC]
- azimexon [MeSH concept]
- azimexon [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- azimexon [Substance BNPC]
- azimexon [MeSH concept]
- azimexon [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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