Preferred Label : Pyrogenicity/Endotoxin Assessment;
NCIt related terms : Pyrogenicity/Endotoxin;
NCIt definition : Tests to measure the ability of a substance to produce an endotoxin or febrile and/or
inflammatory reaction in response to administration of a substance.;
Alternative definition : PQCMC: Tests designed to limit to an acceptable level the risks of febrile reaction
in the patient to the administration, by injection, of the product concerned. The
test involves measuring the rise in temperature of rabbits following the intravenous
injection of a test solution and is designed for products that can be tolerated by
the test rabbit in a dose not to exceed 10 mL/kg injected intravenously within a period
of NMT 10 min.;
NCI Metathesaurus CUI : CL521824;
Origin ID : C133983;
UMLS CUI : C4524980;
Semantic type(s)
- concept_is_in_subset
