Aminothiadiazole

Preferred Label : Aminothiadiazole;

NCIt synonyms : ATDA; 1,3, 4-Thiadiazol-2-amine (9CI); 2-Aminothiadiazole; 2-Amino-1-thia-3,4-diazole; Amino 134-Thiadiazole;

NCIt related terms : 1,3,4-Thiadiazole, 2-amino; 2-Amino-1,3,4-thiadiazole; 1,3, 4-Thiadiazole, 2-amino- (8CI); FDA 0084;

NCIt definition : A synthetic derivative of nicotinamide adenine dinucleotide (NAD). Aminothiadiazole competitively inhibits inosine 5-monophosphate dehydrogenase, thereby disrupting the regulation of cell proliferation and differentiation in a number of cells. This agent is also a selective human adenosine A3 receptor antagonist. (NCI04);

UNII : 6L41AOK74P;

CAS number : 4005-51-0;

Molecule name : FDA 0084;

NSC code : 4728;

Codes from synonyms : NSC0004728;

Details

Origin ID

C1335;

UMLS CUI

C0092419;

Currated CISMeF NLP mapping
- 1,3,4-thiadiazol-2-amine [Substance BNPC]
- 2-amino-1,3,4-thiadiazole [MeSH concept]
- 2-amino-1,3,4-thiadiazole [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- 1,3,4-thiadiazol-2-amine [Substance BNPC]
- 2-amino-1,3,4-thiadiazole [MeSH concept]
- 2-amino-1,3,4-thiadiazole [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_target
- Inosine Monophosphate Dehydrogenase [NCIt concept]

Keyword's position in hierarchy(ies) :

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