NCIt related terms : etidronate; EHDP; Ethane-1-hydroxy-1,1-diphosphonic acid;
NCIt definition : As a member of the family of drugs known as bisphosphonates, etidronate differs from
endogenous pyrophosphate in its resistance to enzymatic hydrolysis. This agent adsorbs
to hydroxyapatite cells and reduces the number of osteoclasts, thereby inhibiting
abnormal bone resorption. Etidronate may also directly stimulate bone formation by
osteoblasts. (NCI);
Alternative definition : NCI-GLOSS: A drug that belongs to the family of drugs called bisphosphonates. Bisphosphonates
are used as treatment for hypercalcemia (abnormally high levels of calcium in the
blood) and for cancer that has spread to the bone (bone metastases).;