Preferred Label : Stage IV Sinonasal Cancer AJCC v8;
NCIt synonyms : Stage IV Nasal Cavity and Paranasal Sinus Carcinoma AJCC v8; Stage IV Nasal Cavity and Paranasal Sinus Cancer AJCC v8; Stage IV Sinonasal Carcinoma AJCC v8;
NCIt related terms : Stage IV Nasal Cavity and Paranasal Sinus Cancer;
NCIt definition : Stage IV includes: IVA: (T4a, N0, M0); (T4a, N1, M0); (T1, N2, M0); (T2, N2, M0);
(T3, N2, M0); (T4a, N2, M0); IVB: (T4b, Any N, M0); (Any T, N3, M0); IVC: (Any T,
Any N, M1). T4a: Maxillary sinus: Moderately advanced local disease. Tumor invades
anterior orbital contents, skin of cheek, pterygoid plates, infratemporal fossa, cribriform
plate, sphenoid or frontal sinuses. Nasal cavity and ethmoid sinus: Moderately advanced
local disease. Tumor invades any of the following: anterior orbital contents, skin
of nose or cheek, minimal extension to anterior cranial fossa, pterygoid plates, sphenoid
or frontal sinuses. T4b: Very advanced local disease. Tumor invades any of the following:
orbital apex, dura, brain, middle cranial fossa, cranial nerves other than maxillary
division of trigeminal nerve (V2), nasopharynx, or clivus. T1: Maxillary sinus: Tumor
limited to the maxillary sinus mucosa with no erosion or destruction of bone. Nasal
cavity and ethmoid sinus: Tumor restricted to any one subsite, with or without bony
invasion. T2: Maxillary sinus: Tumor causing bone erosion or destruction including
extension into the hard palate and/or middle nasal meatus, except extension to posterior
wall of maxillary sinus and pterygoid plates. Nasal cavity and ethmoid sinus: Tumor
invading two subsites in a single region or extending to involve an adjacent region
within the nasoethmoidal complex, with or without bony invasion. T3: Maxillary sinus:
Tumor invading any of the following: bone of the posterior wall of maxillary sinus,
subcutaneous tissues, floor or medial wall of orbit, pterygoid fossa, or ethmoid sinuses.
Nasal cavity and ethmoid sinus: Tumor invading the medial wall or floor of the orbit,
maxillary sinus, palate, or cribriform plate. N0: No regional lymph node metastasis.
N1: Metastasis in a single ipsilateral lymph node, 3 cm or less in greatest dimension
and ENE(-). N2: Metastasis in a single ipsilateral lymph node, 3 cm or smaller in
greatest dimension and ENE( ); or metastasis in a single ipsilateral lymph node larger
than 3 cm but not larger than 6 cm in greatest dimension and ENE(-); or metastases
in multiple ipsilateral lymph nodes , none larger than 6 cm in greatest dimension
and ENE(-); or metastases in bilateral or contralateral lymph nodes, none larger than
6 cm in greatest dimension and ENE(-). N3: Metastasis in a lymph node larger than
6 cm in greatest dimension and ENE(-); or metastasis in a single ipsilateral node
larger than 3 cm in greatest dimension and ENE( ); or metastases in multiple ipsilateral,
contralateral or bilateral nodes, any with ENE( ). M0: No distant metastasis. M1:
Distant metastasis. (AJCC 8th ed.);
Neoplastic status : Malignant;
NCI Metathesaurus CUI : CL520512;
Origin ID : C133079;
UMLS CUI : C4521626;
Disease excludes abnormal cell
- Has associated anatomic sites
- Semantic type(s)
- concept_is_in_subset
- disease_excludes_finding
- disease_has_abnormal_cell
- disease_has_finding
- disease_has_normal_cell_origin
- disease_has_normal_tissue_origin
- disease_has_primary_anatomic_site
- disease_is_stage
