Iodine I 131 Iodocholesterol

Preferred Label : Iodine I 131 Iodocholesterol;

NCIt synonyms : Iodine 131 Iodocholesterol; Iodocholesterol I 131; Cholest-5-en-3-ol, 19(Iodo-(sup 131)I)-, (3beta)-; Iodocholesterol (131 I); I-131 Iodocholesterol; Iodine I-131 Iodocholesterol; Iodocholesterol (131I);

NCIt related terms : IODOCHOLESTEROL I-131;

NCIt definition : A radioiodine-labeled cholesterol analogue with diagnostic imaging activity upon scintigraphy. Upon administration, iodine I 131 iodocholesterol accumulates in tissues where steroid hormones are produced, including the adrenal glands and, to a lesser extent, the ovaries and the testes. After binding to low-density lipoprotein (LDL) receptors on adrenocortical cells, this agent is internalized. As cholesterol is the precursor for all adrenocortical steroid hormones, areas of hormonal hypersecretion, can be visualized using scintigraphy and the adrenocortical function can be assessed.;

UNII : C5F4248GPJ;

InChIKey : FIOAEFCJGZJUPW-ODFYUTSGSA-N;

CAS number : 42220-21-3;

Details

Origin ID

C133023;

UMLS CUI

C0304983;

Automatic exact mappings (from CISMeF team)
- Iodine-131 iodocholesterol [Radlex concept]
- Iodocholesterol (131I) [ICHI extension code]
- iodocholesterol (131i) [ATC Code]
Currated CISMeF NLP mapping
- Iodocholesterol (131-I) (substance) [SNOMED CT concept]
- Iodocholesterol (131I) [ICD-11 Extension code]
- iodocholesterol i131 [SNOMED Notion]
Semantic type(s)
- Indicator, Reagent, or Diagnostic Aid [UMLS semantic type]
- Inorganic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Iodocholesterol (131-I) (substance) [SNOMED CT concept]
- iodocholesterol i131 [SNOMED Notion]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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