Preferred Label : Stage IVA Lip and Oral Cavity Cancer AJCC v8;
NCIt synonyms : Stage IVA Lip and Oral Cavity Carcinoma AJCC v8;
NCIt related terms : Stage IVA Lip and Oral Cavity Cancer;
NCIt definition : Stage IVA includes: (T4a, N0, M0); (T4a, N1, M0); (T1, N2, M0); (T2, N2, M0); (T3,
N2, M0); (T4a, N2, M0). T4a (lip): Tumor invades through cortical bone or involves
the inferior alveolar nerve, floor of mouth, or skin of face (i.e., chin or nose).
T4a (oral cavity): Tumor invades adjacent structures only (e.g., through cortical
bone of the mandible or maxilla, or involves the maxillary sinus or skin of face).
Note: Superficial erosion of bone/tooth socket (alone) by a gingival primary is not
sufficient to classify a tumor as T4. T1: Tumor size 2 cm or less in greatest dimension
and 5 mm or less DOI. T2: Tumor size 2 cm or less in greatest dimension, DOI greater
than 5 mm and equal or less than 10 mm or tumor greater than 2 cm but 4 cm or less
in greatest dimension and 10 mm or less DOI. T3: Tumor size greater than 4 cm or any
tumor greater than 10 mm DOI. N0: No regional lymph node metastasis. N1: Metastasis
in a single ipsilateral lymph node, 3 cm or smaller in greatest dimension and ENE(-).
N2: Metastasis in a single ipsilateral lymph node, 3 cm or smaller in greatest dimension
and ENE( ); or larger than 3 cm but not larger than 6 cm in greatest dimension and
ENE (-); or metastases in multiple ipsilateral lymph nodes, none larger than 6 cm
in greatest dimension and ENE(-); or metastases in bilateral or contralateral lymph
nodes, none larger than 6 cm in greatest dimension, ENE(-). M0: No distant metastasis.
(AJCC 8th Ed.);
Neoplastic status : Malignant;
NCI Metathesaurus CUI : CL520514;
Origin ID : C132733;
UMLS CUI : C4331337;
Disease excludes abnormal cell
Has associated anatomic sites
Semantic type(s)
concept_is_in_subset
disease_excludes_finding
disease_has_abnormal_cell
disease_has_finding
disease_has_normal_cell_origin
disease_has_normal_tissue_origin
disease_has_primary_anatomic_site
disease_is_stage