NCIt definition : A stilbene derivative labeled with the positron-emitting isotope fluorine F 18, that
may be used for positron emission tomography (PET) detection of beta-amyloid neuritic
plaques and other amyloid protein deposits. Upon administration, F 18-florbetaben
exhibits differential retention in regions that contain certain amyloid deposits.
Differences in signal intensity between tissues showing specific and non-specific
uptake of F 18-florbetaben allows for the detection of amyloid neuritic plaques in
patients being evaluated for Alzheimer's disease, and potentially the detection of
amyloid deposits in amyloidosis.;