Preferred Label : Calculated Panel Reactive Antibody Measurement;
NCIt synonyms : CPRA Measurement;
NCIt related terms : Calculated Panel Reactive Antibody; PRABC;
NCIt definition : The determination of the calculated panel reactive antibody (CPRA), which is based
on the number/type of unacceptable HLA antigens to which an organ recipient has been
sensitized, and which algorithmically estimates the level of sensitization in the
recipient. The CPRA is computed from HLA antigen frequencies in a given donor population
using both anti-HLA class I and class II antibody specificities; it also represents
the percentage of actual organ donors that express one or more unacceptable HLA antigens
to which a recipient may react adversely.;
Alternative definition : CDISC: A measurement of the calculated panel reactive antibody, which is based on
the number/type of unacceptable HLA antigens to which an organ recipient has been
sensitized, and which algorithmically estimates the level of sensitization in the
recipient. The CPRA is computed from HLA antigen frequencies in a given donor population
using both anti-HLA class I and class II antibody specificities; it also represents
the percentage of actual organ donors that express one or more unacceptable HLA antigens
to which a recipient may react adversely.;
NCI Metathesaurus CUI : CL521664;
Origin ID : C132381;
UMLS CUI : C4324744;
See also inter- (CISMeF)
- Semantic type(s)
- concept_is_in_subset
