Cyclooxygenase Inhibitor

Preferred Label : Cyclooxygenase Inhibitor;

NCIt synonyms : Clyclooxygenases Inhibitor; Prostaglandin G/H Synthase Inhibitor;

NCIt related terms : COX inhibitor;

NCIt definition : Any agent that inhibits prostaglandin G/H synthase (cyclooxygenase or COX), an enzyme that catalyzes the production of prostanoids, including prostaglandins, prostacyclin and thromboxane, from arachidonic acid. Cyclooxygenase inhibitors are a type of non-steroidal anti-inflammatory drug.;

Alternative definition : NCI-GLOSS: A type of drug that is used to treat inflammation and pain, and is being studied in the prevention and treatment of cancer. COX inhibitors belong to the family of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs).;

ChEBI ID : CHEBI:35544;

Codes from synonyms : CDR0000444986; CDR0000444985;

Details

Origin ID

C1323;

UMLS CUI

C0085387;

Automatic exact mappings (from CISMeF team)
- Prostaglandin-endoperoxide synthase inhibitor (disposition) [SNOMED CT concept]
- Substance with prostaglandin-endoperoxide synthase inhibitor mechanism of action (substance) [SNOMED CT concept]
Currated CISMeF NLP mapping
- cyclooxygenase inhibitors [MeSH Descriptor]
- cyclooxygenase inhibitors [MeSH concept]
Semantic type(s)
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Substance with prostaglandin-endoperoxide synthase inhibitor mechanism of action (substance) [SNOMED CT concept]
- cyclooxygenase inhibitors [MeSH concept]
- cyclooxygenase inhibitors [MeSH Descriptor]

Keyword's position in hierarchy(ies) :

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