F-Actin-Capping Protein Subunit Alpha-2

Preferred Label : F-Actin-Capping Protein Subunit Alpha-2;

NCIt synonyms : F-Actin Capping Protein Alpha-2 Subunit; CapZ Alpha-2; CAPZA2;

NCIt definition : F-actin-capping protein subunit alpha-2 (286 aa, 33 kDa) is encoded by the human CAPZA2 gene. This protein is involved in the inhibition of actin polymerization and depolymerization.;

NCIt note : F-actin-capping protein subunit alpha-2 binds to F-actin-capping protein subunit beta to form the F-actin-capping protein. The F-actin-capping protein is a component of the WASH complex, which regulates actin branching. (UniProt);

Details

Origin ID

C132074;

UMLS CUI

C1565245;

Automatic exact mappings (from CISMeF team)
- Capping protein, alpha-2 [OMIM gene]
- capping actin protein of muscle Z-line subunit alpha 2 [HGNC gene]
OMIM relation
- Capping protein, alpha-2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- CAPZA2 protein, human [MeSH Supplementary Concept]
- CAPZA2 protein, human [MeSH concept]
gene_encodes_gene_product
- CAPZA2 Gene [NCIt concept]
- Cytoskeletal Gene [NCIt concept]
- Structural Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoskeleton [NCIt concept]
gene_product_has_biochemical_function
- Actin-Binding Protein [NCIt concept]
gene_product_is_element_in_pathway
- Endocytosis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Movement Process [NCIt concept]
- Cytoskeletal Modeling [NCIt concept]
- Cytoskeletal Process [NCIt concept]
- Regulation of Cell Shape [NCIt concept]

Keyword's position in hierarchy(ies) :

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