USP22 wt Allele

Preferred Label : USP22 wt Allele;

NCIt synonyms : KIAA1063; Ubiquitin Specific Peptidase 22 wt Allele; USP3L;

NCIt definition : Human USP22 wild-type allele is located in the vicinity of 17p11.2 and is approximately 44 kb in length. This allele, which encodes ubiquitin carboxyl-terminal hydrolase 22 protein, is involved in the removal of ubiquitin from histone H2 proteins.;

NCIt note : Deletion mutations in the USP22 gene may be associated with squamous cell lung carcinomas. (Nature Genetics. 2016; 48:607-616);

NCI Metathesaurus CUI : CL520264;

GenBank Accession Number : AB028986;

Details

Origin ID

C132057;

UMLS CUI

C4321280;

Automatic exact mappings (from CISMeF team)
- Ubiquitin-specific protease 22 [OMIM gene]
OMIM relation
- Ubiquitin-specific protease 22 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 17p11.2 [NCIt concept]
gene_plays_role_in_process
- Deubiquitination [NCIt concept]
- Hydrolysis [NCIt concept]
- Proteolysis [NCIt concept]
- Transcriptional Activation [NCIt concept]

Keyword's position in hierarchy(ies) :

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