Recombinant Interleukin 10

Preferred Label : Recombinant Interleukin 10;

NCIt synonyms : B cell-derived T cell growth factor; Cytokine Synthesis Inhibitory Factor; Interleukin-10; IL-10; CSIF; Therapeutic Interleukin 10;

NCIt definition : A recombinant cytokine chemically identical to or similar to interleukin-10 (IL-10) secreted by certain leukocytes with immunomodulatory activities. IL-10 is an anti-inflammatory cytokine, capable of inhibiting synthesis of pro-inflammatory cytokines, such as Interferon-gamma, IL-2, IL-3, TNF-alpha, and GM-CSF. However, it also has stimulatory effects on certain T cells, mast cells, and B cells, as well as inducing expression of class II major histocompatibility complex.;

CAS number : 130068-27-8;

Details

Origin ID

C1320;

UMLS CUI

C1522550;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
Validated automatic mappings to NTBT
- Interleukin 10 [LOINC component]
- Interleukin-10 [FMA entity]
- Interleukin-10 [MeSH Descriptor]
- Interleukin-10 [MeSH concept]
- Interleukin-10 (substance) [SNOMED CT concept]
- interleukin 10 [COVID-19 Thesaurus concept]
- interleukin-10 [SNOMED Notion]
chemical_or_drug_has_physiologic_effect
- Immunopotentiation [NCIt concept]
- Inhibition of Cell Proliferation [NCIt concept]
concept_is_in_subset
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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