Preferred Label : Recombinant Interleukin 10;
NCIt synonyms : B cell-derived T cell growth factor; Cytokine Synthesis Inhibitory Factor; Interleukin-10; IL-10; CSIF; Therapeutic Interleukin 10;
NCIt definition : A recombinant cytokine chemically identical to or similar to interleukin-10 (IL-10)
secreted by certain leukocytes with immunomodulatory activities. IL-10 is an anti-inflammatory
cytokine, capable of inhibiting synthesis of pro-inflammatory cytokines, such as Interferon-gamma,
IL-2, IL-3, TNF-alpha, and GM-CSF. However, it also has stimulatory effects on certain
T cells, mast cells, and B cells, as well as inducing expression of class II major
histocompatibility complex.;
CAS number : 130068-27-8; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 130068-27-8
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G-SRS /a ;
Origin ID : C1320;
UMLS CUI : C1522550;
- Semantic type(s)
- Validated automatic mappings to NTBT
- chemical_or_drug_has_physiologic_effect
- concept_is_in_subset