Lithium Carbonate

Preferred Label : Lithium Carbonate;

NCIt synonyms : Lithium;

NCIt related terms : Lithane; Lithotabs; Lithonate; Lithobid; Eskalith;

NCIt definition : The carbonate salt of lithium, a soft alkali metal, with antimanic and hematopoietic activities. Lithium interferes with transmembrane sodium exchange in nerve cells by affecting sodium, potassium-stimulated adenosine triphosphatase (Na , K -ATPase); alters the release of neurotransmitters; affects cyclic adenosine monophosphate (cAMP) concentrations; and blocks inositol metabolism resulting in depletion of cellular inositol and inhibition of phospholipase C-mediated signal transduction. The exact mechanism through which lithium exerts its mood-stabilizing effect has not been established. In addition, lithium stimulates granulocytopoiesis and appears to increase the level of pluripotent hematopoietic stem cells by stimulating the release of hematopoietic cytokines and/or directly acting on hematopoietic stem cells.;

UNII : 2BMD2GNA4V;

InChIKey : XGZVUEUWXADBQD-UHFFFAOYSA-L;

CAS number : 554-13-2;

Drug name : Lithotabs; Lithane; Eskalith; Lithonate; Lithobid; Escalith;

Chemical formula : CO3.2Li;

NSC code : 16895;

ChEBI ID : CHEBI:6504;

Codes from synonyms : NSC0016895;

Details

Origin ID

C1318;

UMLS CUI

C0085217;

Automatic exact mappings (from CISMeF team)
- Lithium [DeCS]
- Lithium [ICD-11 Extension code]
- Lithium:SCnc:Pt:Ser/Plas:Qn: [LOINC code]
- lithium [EMDN type]
- lithium [medical devices type]
- lithium [ATC Code]
- lithium [Radlex concept]
- pressure ulcer [MeSH Descriptor]
False automatic mappings
- On lithium (finding) [SNOMED CT concept]
See also inter- (CISMeF)
- Product containing lithium carbonate (medicinal product) [SNOMED CT concept]
- lithium [ATC Code]
Semantic type(s)
- Inorganic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Lithium [Bloc CIM-11]
- Lithium carbonate (substance) [SNOMED CT concept]
- Product containing lithium carbonate (medicinal product) [SNOMED CT concept]
- lithium carbonate [Substance BNPC]
- lithium carbonate [MeSH concept]
- lithium carbonate [MeSH Descriptor]
- lithium carbonate [SNOMED Notion]
Validated automatic mappings to NTBT
- Lithium [SMS substance]
- Lithium [LOINC component]
- Lithium (substance) [SNOMED CT concept]
- lithium [Substance BNPC]
- lithium [MeSH Descriptor]
- lithium [MeSH concept]
- lithium, nos [SNOMED Notion]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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