Preferred Label : Non-Fucosylated Umbilical Cord Blood Regulatory T-cells;
NCIt synonyms : Non-Fucosylated Umbilical Cord Blood Tregs; Non-Fucosylated UCB Regulatory T-cells; Non-Fucosylated UCB Tregs;
NCIt definition : A preparation of non-fucosylated regulatory T-lymphocytes (Tregs) allogeneically derived
from umbilical cord blood (UCB), with potential immunomodulating activity. Tregs are
essential in maintaining immunologic homeostasis, preventing autoimmunity, through
the suppression of self-reactive T-cells, and they may induce tolerance to allogeneic
organ transplants, including hematopoetic stem cell transplants (HSCTs). Administration
of the non-fucosylated UCB Tregs upon HSCT may prevent or reduce graft-versus host
disease (GVHD).;
NCI Metathesaurus CUI : CL514526;
Origin ID : C131536;
UMLS CUI : C4330828;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
