MT-RNR2 wt Allele

Preferred Label : MT-RNR2 wt Allele;

NCIt synonyms : Humanin, Mitochondrial Gene; l-rRNA; Ribosomal RNA, Mitochondrial, 16S Gene; Mitochondrially Encoded 16S RNA wt Allele; RNR2; MTRNR2; rRNA, 16S, Mitochondrial Gene; HN; HNM;

NCIt definition : Human MT-RNR2 wild-type allele is located within the circular mitochondrial (MT) chromosome and is approximately 2 kb in length. This allele, which encodes both 16S mitochondrial ribosomal RNA and humanin protein, is involved in mitochondrial protein translation and the negative regulation of apoptosis.;

NCIt note : Other small humanin-like peptides (SHLPs) that are encoded by the MT-RNR2 gene have been described and may also affect cell viability. (Aging (Albany NY). 2016; 8: 796-809.);

NCI Metathesaurus CUI : CL514311;

GenBank Accession Number : NC_012920;

PubMed : 27070352;

Details

Origin ID

C131259;

UMLS CUI

C4319728;

Automatic exact mappings (from CISMeF team)
- Ribosomal rna 2 [OMIM gene]
- Ribosomal rna, mitochondrial, 16s [OMIM gene]
- dynein-driven meiotic oscillatory nuclear movement [GO term]
OMIM relation
- Ribosomal rna, mitochondrial, 16s [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_plays_role_in_process
- Chemotaxis Induction [NCIt concept]
- Negative Regulation of Apoptosis [NCIt concept]
- Translation Process [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients