Rho GTPase-Activating Protein 32

Preferred Label : Rho GTPase-Activating Protein 32;

NCIt synonyms : Brain-Specific Rho GTPase-Activating Protein; p250GAP; p200RhoGAP; GAB-Associated Cdc42/Rac GTPase-Activating Protein; GC-GAP; GAB-Associated CDC42; PX-RICS; GTPase-Activating Protein For Cdc42 and Rac1; Brain-Specific Rho GTP-Ase-Activating Protein; RhoGAP Involved in the Beta-Catenin-N-Cadherin and NMDA Receptor Signaling; Rho-Type GTPase-Activating Protein 32; Rho GTPase Involved In Beta-Catenin, N-Cadherin, and NMDA Receptor Signaling; Rho/Cdc42/Rac GTPase-Activating Protein RICS; GTPase Interacting With TrkA; GTPase Regulator Interacting With TrkA;

NCIt definition : Rho GTPase-activating protein 32 (2087 aa, 231 kDa) is encoded by the human ARHGAP32 gene. This protein is involved in the regulation of signaling mediated by both Rho family GTPases and the NMDA receptor.;

NCIt note : UniProt considers the PX-RICS isoform the canonical form of the protein.;

Details

Origin ID

C131141;

UMLS CUI

C4318410;

Automatic exact mappings (from CISMeF team)
- Rho gtpase involved in beta-catenin, n-cadherin, and nmda receptor signaling [OMIM gene]
OMIM relation
- Rho gtpase involved in beta-catenin, n-cadherin, and nmda receptor signaling [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- ARHGAP32 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- ARHGAP32 Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_associated_anatomy
- Postsynaptic Membrane [NCIt concept]
gene_product_plays_role_in_biological_process
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Neural Development [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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