ARHGAP32 wt Allele

Preferred Label : ARHGAP32 wt Allele;

NCIt synonyms : PX-RICS; GRIT; p250GAP; p200RhoGAP; Rho GTPase Activating Protein 32 wt Allele; GC-GAP; KIAA0712; RICS; MGC1892;

NCIt definition : Human ARHGAP32 wild-type allele is located in the vicinity of 11q24.3 and is approximately 314 kb in length. This allele, which encodes Rho GTPase-activating protein 32, plays a role in the modulation of both NMDA receptor signaling and small GTPase activity. Deletion of the chromosomal region containing the gene is associated with a subset of Jacobsen syndrome patients that exhibit autism spectrum disorder.;

NCI Metathesaurus CUI : CL513464;

GenBank Accession Number : AB018255;

PubMed : 26979507;

Details

Origin ID

C131140;

UMLS CUI

C4321463;

Automatic exact mappings (from CISMeF team)
- Grit (substance) [SNOMED CT concept]
- Rho gtpase involved in beta-catenin, n-cadherin, and nmda receptor signaling [OMIM gene]
- grit [IUPAC Term]
OMIM relation
- Rho gtpase involved in beta-catenin, n-cadherin, and nmda receptor signaling [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_plays_role_in_process
- Neural Development [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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