Alternative definition : NICHD: An autosomal recessive condition caused by mutation(s) in the INSR gene, encoding
the insulin receptor, and characterized by insulin resistance, intrauterine growth
restriction (IUGR) and/or failure to thrive, muscle atrophy, hypertrichosis, and distinctive
facial features; the condition is typically diagnosed early in life, with death usually
occurring before the third decade of life. The symptoms and course of this syndrome
are moderately severe as compared to the other two syndromes on the spectrum: Insulin
Resistant Diabetes Mellitus with Acanthosis Nigricans and Hyperandrogenism, and Donohue
Syndrome.;