Preferred Label : Recombinant Pleiotrophin;
NCIt synonyms : Heparin-Binding Growth Factor-8; HARP; Heparin-Binding Neurotrophic Factor; OSF-1; Pleiotrophin; HBNF; HBGF-8; Heparin Affin Regulatory Peptide; Osteoblast Specific Factor 1; Recombinant Heparin-Binding Neurotrophic Factor;
NCIt definition : A recombinant form of the heparin-binding cytokine pleiotrophin. Developmentally regulated,
pleiotrophin functions as a growth factor during embryogenesis and the neonatal period,
contributing to trophoblast formation, organ development, bone formation, and early
brain development by inducing the differentiation and proliferation of neuronal tissue.
Expressed in certain tumor cell types, this agent may stimulate tumor cell growth,
angiogenesis, and metastasis. (NCI04);
CAS number : 134034-50-7;
Origin ID : C1307;
UMLS CUI : C1524097;
Currated CISMeF NLP mapping
- Semantic type(s)
