Preferred Label : Methyl 2,5-dihydroxycinnamate;
NCIt synonyms : 3-(2,5-Dihydroxyphenyl)-2-propenoic Acid Methyl Ester; Methyl 3-(2,5-dihydroxyphenyl)-2-propenoate; 2,5-Dihydroxycinnamic Acid Methyl Ester; 2,4-Dihydroxymethylcinnamate; Erbstatin Analog;
NCIt related terms : Methyl-2,5-dihydroxycinnamate;
NCIt definition : A cell-permeable analog of erbstatin, a compound isolated from Streptomyces that inhibits
the autophosphorylation of epidermal growth factor receptor. Erbstatin analogue competitively
inhibits epidermal growth factor receptor-associated tyrosine kinase, inhibiting the
activation of v-abl tyrosine kinase. In addition, this agent has induced apoptosis
in mouse thymocytes and inhibits the G2/M phase of the cell cycle. (NCI);
CAS number : 63177-57-1;
Molecule name : ALX-270-098; BML-EI146;
Chemical formula : C10H10O4;
Codes from synonyms : 30473;
PubMed : 8242767;
Origin ID : C1305;
UMLS CUI : C0083406;
Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
