B Acute Lymphoblastic Leukemia, BCR-ABL1-Like

Preferred Label : B Acute Lymphoblastic Leukemia, BCR-ABL1-Like;

Obsolete resource : true;

NCIt synonyms : B Acute Lymphoblastic Leukemia with Translocations Involving Tyrosine Kinases or Cytokine Receptors; B-ALL with Translocations Involving Tyrosine Kinases or Cytokine Receptors; B-Cell Acute Lymphoblastic Leukemia, BCR-ABL1-Like;

NCIt definition : B acute lymphoblastic leukemia with translocations involving tyrosine kinases, or translocations involving either the cytokine receptor-like factor 2 (CRLF2) or rearrangements leading to truncation and activation of the erythropoietin receptor (EPOR). It is associated with an adverse prognosis.;

NCIt note : See 'B Acute Lymphoblastic Leukemia with BCR-ABL1-Like Features(C121974)';

Neoplastic status : Malignant;

Concept status : Retired_Concept;

NCI Metathesaurus CUI : CL512918;

Details

Origin ID

C129788;

UMLS CUI

C4329381;

Disease may have findings
- Bone Pain [NCIt concept]
- Extensive Bone Marrow and Blood Involvement [NCIt concept]
- Granulocytopenia [NCIt concept]
- Hepatomegaly [NCIt concept]
- Lymphadenopathy [NCIt concept]
- Splenomegaly [NCIt concept]
- Thrombocytopenia [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Chronic Clinical Course [NCIt concept]
- Solid Growth Pattern [NCIt concept]
disease_has_finding
- Malignant Cellular Infiltrate [NCIt concept]
- Recurrent Genetic Abnormalities Present [NCIt concept]
- Translocations Involving Tyrosine Kinases or Cytokine Receptors Present [NCIt concept]
- Unfavorable Clinical Outcome [NCIt concept]
disease_has_primary_anatomic_site
- Bone Marrow [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]

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