Preferred Label : Bifidobacterium animalis/Lactobacillus rhamnosus Probiotic Supplement;
NCIt synonyms : Bifidobacterium animalis/Lactobacillus rhamnosus Probiotic; Lactobacillus rhamnosus GG/ Bifidobacterium animalis subsp. lactis BB-12; BB-12/LGG; Lactobacillus rhamnosus/Bifidobacterium animalis subsp. lactis;
NCIt definition : An orally bioavailable, probiotic supplement containing the non-pathogenic microorganisms
Bifidobacterium animalis and Lactobacillus rhamnosus subspecies lactis with potential
immunomodulating, anti-diarrheal and mucosal protective activities. Upon oral ingestion,
the naturally-occurring bacterial components in Bifidobacterium animalis/Lactobacillus
rhamnosus subspecies lactis probiotic supplement may improve digestion and help to
maintain adequate colonization of the gastrointestinal (GI) tract by modulating the
composition of the normal microflora. They produce lactic acid, hydrogen peroxide
and other substances during fermentation, thereby creating an acidic environment that
is unfavorable for pathogens. During colonization in the GI tract, the bacteria may
also form a protective intestinal barrier, which may prevent damage to the mucosal
epithelium, maintains the integrity of the epithelial barrier from potential damage
by toxins and certain chemicals, and reduces the potential for attachment of pathogens.
This further protects against bacterial translocation and infection. In addition,
this agent may reduce the secretion of pro-inflammatory cytokines and may potentiate
natural and acquired immunity. Altogether, this may increase immunity, prevent GI
mucosal damage, malabsorption, inflammation, and reduce diarrhea, such as diarrhea
induced by inflammation and GI mucosa-damaging agents.;
Drug name : PROBIO-FIX INUM;
NCI Metathesaurus CUI : CL512602;
Origin ID : C129649;
UMLS CUI : C4329455;
Semantic type(s)
- concept_is_in_subset
