NCIt definition : Human TC22 allele is a variant form of the human TPM3 gene located 1q21.2 and is approximately
39 kb in length. This allele, which encodes tropomyosin alpha-3 chain isoform 3, may
be involved in carcinogenesis in the colon.;
NCIt note : The TC22 allele contains an alternative exon 9 sequence, which encodes amino acids
222-247.;