Preferred Label : TNFd3 Repeat;
NCIt synonyms : TNFd3 Haplotype; TNFd3 Microsatellite; TNFd3 Allele;
NCIt definition : One of 6 forms of the TNFd microsatellite repeat, which consists of three regions
containing the repetitive dinucleotide sequence, (GA)n, each separated by a single
diguanine repeat and is located 15 kb downstream of the TNF gene in intron 3 of the
LST1 gene. TNFd3 three repeat regions contain 13 GA repeats, 9 GA repeats and 3 GA
repeats, respectively. The TNFd3 polymorphism may influence tumor necrosis factor
protein expression and may be associated with increased susceptibility to either inflammatory
diseases or post-transplant complications.;
NCI Metathesaurus CUI : CL512722;
PubMed : 14735154;
Origin ID : C129377;
UMLS CUI : C4331375;
Semantic type(s)
- concept_is_in_subset
