Recombinant Macrophage Colony-Stimulating Factor

Preferred Label : Recombinant Macrophage Colony-Stimulating Factor;

NCIt synonyms : Recombinant Colony Stimulating Factor 1; Macrophage Colony Stimulating Factor; rM-CSF;

NCIt definition : A recombinant therapeutic agent which is chemically identical to or similar to the endogenous protein cytokine macrophage colony-stimulating factor (M-CSF). Synthesized endogenously by mesenchymal cells, M-CSF stimulates the survival, proliferation, and differentiation of hematopoietic cells of the monocyte-macrophage series and can reverse treatment-related neutropenias. Recombinant M-CSF may also enhance antigen presentation and activate antitumoral cytotoxic T-cells.;

CAS number : 81627-83-0;

Details

Origin ID

C1290;

UMLS CUI

C1524095;

Currated CISMeF NLP mapping
- Colony-stimulating factor, macrophage (substance) [SNOMED CT concept]
- Macrophage colony-stimulating factor [LOINC component]
- colony-stimulating factor, macrophage [SNOMED Notion]
- macrophage Colony-Stimulating factor [MeSH concept]
- macrophage colony-stimulating factor [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
is_component_of_chemotherapy_regimen
- Interferon Gamma/Macrophage Colony-Stimulating Factor [NCIt concept]
- Interleukin-2/Macrophage Colony-Stimulating Factor [NCIt concept]

Keyword's position in hierarchy(ies) :

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