Preferred Label : Thrombomodulin Alfa;
NCIt synonyms : Thrombomodulin (Human 498-Amino Acid Fragment); 1-498-Thrombomodulin (Human Clone TMP26/TMJ1 Protein Moiety Reduced);
NCIt definition : A recombinant, soluble form of the human protein thrombomodulin, with potential anticoagulant
activity. Upon administration, thrombomodulin binds to thrombin, which stimulates
the activation of protein C. Activated protein C (APC) degrades factor Va and Factor
VIIa in the presence of the cofactor protein S, inhibits thrombin formation, and prevents
both thrombin-mediated coagulation and further clot formation.;
UNII : 2VU8WT49WX;
Drug name : Recomodulin;
Molecule name : ART 123; ART-123;
Origin ID : C128894;
UMLS CUI : C4284401;
Semantic type(s)
concept_is_in_subset