Pegteograstim - CISMeF

Preferred Label : Pegteograstim;

NCIt definition : An analogue of pegfilgrastim, a recombinant, pegylated form of endogenous human granulocyte colony-stimulating factor (G-CSF), with hematopoietic activity. Similar to endogenous G-CSF, this agent binds to and activates specific cell surface receptors, and stimulates neutrophil progenitor proliferation, differentiation and selected neutrophil functions. Pegteograstim may prevent and shorten the duration of chemotherapy-induced neutropenia (CIN). Pegylation of teograstim increases the half-life of this agent.;

UNII : 71V0XKJ0WZ;

CAS number : 1329602-23-4;

Drug name : Neurapeg;

NCI Metathesaurus CUI : CL512491;

Details

Origin ID

C128891;

UMLS CUI

C4288415;

Currated CISMeF NLP mapping
- Pegteograstim [ICD-11 Extension code]
- Pegteograstim [SMS substance]
Semantic type(s)
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- pegteograstim [ATC Code]
Validated automatic mappings to BTNT
- pegteograstim [ATC Code]
chemical_or_drug_affects_cell_type_or_tissue
- Hematopoietic Stem Cell [NCIt concept]
chemical_or_drug_affects_gene_product
- GM-CSF Receptor [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Cytokine Receptor Activation [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Positive Regulation of Cell Differentiation [NCIt concept]
- Receptor Activation Process [NCIt concept]
- Stimulation of Cell Proliferation [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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