Preferred Label : GAIA Level 2 Prenatally Diagnosed Congenital Microcephaly;
NCIt synonyms : Global Alignment of Immunization safety Assessment in pregnancy Level 2 Prenatally
Diagnosed Congenital Microcephaly;
NCIt related terms : Level 2 Prenatally Diagnosed Congenital Microcephaly;
NCIt definition : GAIA Level 2 Prenatally Diagnosed Congenital Microcephaly is defined by three criteria:
first, the fetus is at least 24 weeks gestational age (GA) based on last menstrual
period (LMP) date with fundal height and no confirmatory first or second trimester
ultrasound (US) scan; second, a head circumference (HC) measurement either 2 standard
deviations (SD) below the mean or less than the third percentile according to fetal
US examination, using appropriate, standardized reference charts according to GA and
gender for the population (e.g. WHO growth reference charts if GA greater than or
equal to 37 weeks and Intergrowth-21st reference charts for GA 24 to 36 weeks) with
femur length and abdominal circumference concordant with GA assessment; third, confirmation
of microcephaly (i.e., HC 2 SD below the mean or less than 3%) in the fetus by either
at least one additional US after 24 weeks that occurs at least one week after the
first US, OR confirmation of microcephaly by HC measurement with a standard tape measure
at either birth or autopsy.;
Alternative definition : GAIA: Level 2 Prenatally Diagnosed Congenital Microcephaly is defined by three criteria:
first, the fetus is at least 24 weeks gestational age (GA) based on last menstrual
period (LMP) date with fundal height and no confirmatory first or second trimester
ultrasound (US) scan; second, a head circumference (HC) measurement either 2 standard
deviations (SD) below the mean or less than the third percentile according to fetal
US examination, using appropriate, standardized reference charts according to GA and
gender for the population (e.g. WHO growth reference charts if GA greater than or
equal to 37 weeks and Intergrowth-21st reference charts for GA 24 to 36 weeks) with
femur length and abdominal circumference concordant with GA assessment; third, confirmation
of microcephaly (i.e., HC 2 SD below the mean or less than 3%) in the fetus by either
at least one additional US after 24 weeks that occurs at least one week after the
first US, OR confirmation of microcephaly by HC measurement with a standard tape measure
at either birth or autopsy.;
NCI Metathesaurus CUI : CL509116;
Origin ID : C128764;
UMLS CUI : C4289149;
Semantic type(s)
- concept_is_in_subset
