Preferred Label : GAIA Level 1a Prenatally Diagnosed Congenital Microcephaly;
NCIt synonyms : Global Alignment of Immunization safety Assessment in pregnancy Level 1a Prenatally
Diagnosed Congenital Microcephaly;
NCIt related terms : Level 1a Prenatally Diagnosed Congenital Microcephaly;
NCIt definition : GAIA Level 1a Prenatally Diagnosed Congenital Microcephaly is defined by three criteria:
first, the fetus is at least 24 weeks gestational age (GA) based on certain last menstrual
period (LMP) date with confirmatory 1st trimester or 2nd trimester ultrasound (US)
scan OR intrauterine insemination (IUI) or embryo transfer date; second, a head circumference
(HC) measurement either 2 standard deviations (SD) below the mean or less than the
third percentile according to fetal US examination, using appropriate, standardized
reference charts according to GA and gender for the population (e.g. WHO growth reference
charts if GA greater than or equal to 37 weeks and Intergrowth-21st reference charts
for GA 24-36 weeks); third, confirmation of microcephaly (i.e., HC 2 SD below the
mean or less than 3%) in the fetus by either at least one additional US after 24 weeks
that occurs at least one week after the first US, OR confirmation of microcephaly
by HC measurement with a standard tape measure at either birth or autopsy.;
Alternative definition : GAIA: Level 1a Prenatally Diagnosed Congenital Microcephaly is defined by three criteria:
first, the fetus is at least 24 weeks gestational age (GA) based on certain last menstrual
period (LMP) date with confirmatory 1st trimester or 2nd trimester ultrasound (US)
scan OR intrauterine insemination (IUI) or embryo transfer date; second, a head circumference
(HC) measurement either 2 standard deviations (SD) below the mean or less than the
third percentile according to fetal US examination, using appropriate, standardized
reference charts according to GA and gender for the population (e.g. WHO growth reference
charts if GA greater than or equal to 37 weeks and Intergrowth-21st reference charts
for GA 24-36 weeks); third, confirmation of microcephaly (i.e., HC 2 SD below the
mean or less than 3%) in the fetus by either at least one additional US after 24 weeks
that occurs at least one week after the first US, OR confirmation of microcephaly
by HC measurement with a standard tape measure at either birth or autopsy.;
NCI Metathesaurus CUI : CL509111;
Origin ID : C128762;
UMLS CUI : C4289186;
Semantic type(s)
- concept_is_in_subset
