Preferred Label : GAIA Level 2b Postnatally Diagnosed Congenital Microcephaly;
NCIt synonyms : Global Alignment of Immunization safety Assessment in pregnancy Level 2b Postnatally
Diagnosed Congenital Microcephaly;
NCIt related terms : Level 2b Postnatally Diagnosed Congenital Microcephaly;
NCIt definition : GAIA Level 2b Postnatally Diagnosed Congenital Microcephaly is defined by three criteria:
first, a live birth, stillbirth, or spontaneous or therapeutic abortion of at least
24 weeks gestational age (GA), with GA assessed based on uncertain LMP with 2nd trimester
ultrasound (US) scan; second, a head circumference (HC) measurement either 2 standard
deviations (SD) below the mean or less than the third percentile as assessed by GA
and gender, using appropriate, standardized reference charts for the population (e.g.
WHO growth reference charts if GA greater than or equal to 37 weeks and Intergrowth-21st
reference charts for GA 24 to 36 weeks); third, one of the following requirements
is met: a) the measurement is taken within the first 24 hours after birth or at the
end of the pregnancy taking into consideration the molding of the head; OR b) the
measurement is taken greater than 36 hours and up to 6 weeks after birth or the end
of the pregnancy with no apparent post-natal insult resulting in microcephaly.;
Alternative definition : GAIA: Level 2b Postnatally Diagnosed Congenital Microcephaly is defined by three criteria:
first, a live birth, stillbirth, or spontaneous or therapeutic abortion of at least
24 weeks gestational age (GA), with GA assessed based on uncertain LMP with 2nd trimester
ultrasound (US) scan; second, a head circumference (HC) measurement either 2 standard
deviations (SD) below the mean or less than the third percentile as assessed by GA
and gender, using appropriate, standardized reference charts for the population (e.g.
WHO growth reference charts if GA greater than or equal to 37 weeks and Intergrowth-21st
reference charts for GA 24 to 36 weeks); third, one of the following requirements
is met: a) the measurement is taken within the first 24 hours after birth or at the
end of the pregnancy taking into consideration the molding of the head; OR b) the
measurement is taken greater than 36 hours and up to 6 weeks after birth or the end
of the pregnancy with no apparent post-natal insult resulting in microcephaly.;
NCI Metathesaurus CUI : CL509120;
Origin ID : C128759;
UMLS CUI : C4289143;
Semantic type(s)
concept_is_in_subset