Recombinant Granulocyte Colony-Stimulating Factor

Preferred Label : Recombinant Granulocyte Colony-Stimulating Factor;

NCIt synonyms : Recombinant Colony-Stimulating Factor 3; rhG-CSF; Recombinant Granulocyte Colony Stimulating Factor;

NCIt definition : A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine granulocyte colony-stimulating factor (G-CSF). Secreted by monocytes, macrophages and neutrophils and other cells after activation, G-CSF stimulates the proliferation and differentiation of hematopoietic progenitor cells committed to the neutrophil/ granulocyte lineage. (NCI04);

CAS number : 143011-72-7;

Details

Origin ID

C1287;

UMLS CUI

C0376562;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_affects_cell_type_or_tissue
- Hematopoietic Stem Cell [NCIt concept]
chemical_or_drug_affects_gene_product
- GM-CSF Receptor [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Cytokine Receptor Activation [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Positive Regulation of Cell Differentiation [NCIt concept]
- Receptor Activation Process [NCIt concept]
- Stimulation of Cell Proliferation [NCIt concept]
concept_is_in_subset
- NCI Drug Dictionary Terminology [NCIt concept]
is_component_of_chemotherapy_regimen
- Interleukin-2/Stem Cell Factor [NCIt concept]
- Paclitaxel/Cisplatin/Topotecan/G-CSF [NCIt concept]

Keyword's position in hierarchy(ies) :

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