Vulvar Merkel Cell Carcinoma

Preferred Label : Vulvar Merkel Cell Carcinoma;

NCIt definition : A Merkel cell carcinoma that arises from the vulva. It usually presents as a cutaneous nodular lesion. Most small cell neuroendocrine carcinomas of the vulva are Merkel cell carcinomas.;

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL509575;

Details

Origin ID

C128247;

UMLS CUI

C4288003;

Disease excludes abnormal cell
- Large Osteoclastic Giant Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Endothelial Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Disease excludes normal cell origin
- Endothelial Cell [NCIt concept]
Disease may have findings
- Diffuse Pattern [NCIt concept]
- Merkel Cell Polyoma Virus Positive [NCIt concept]
- Nodular Pattern [NCIt concept]
- Trabecular Pattern [NCIt concept]
Excludes anatomical site(s)
- Head and Neck [NCIt concept]
- Lung [NCIt concept]
- Skin [NCIt concept]
Has associated anatomic sites
- Female Reproductive System [NCIt concept]
- Genitourinary System [NCIt concept]
- Integumentary System [NCIt concept]
- Reproductive System [NCIt concept]
- Skin [NCIt concept]
- Vulva [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Favorable Clinical Outcome [NCIt concept]
- Intermediate Grade Neuroendocrine Lesion [NCIt concept]
- Well Differentiated Neuroendocrine Lesion [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Endocrine Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Malignant Neuroendocrine Cell [NCIt concept]
- Malignant Neuroendocrine Small Round Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Endocrine Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Neuroendocrine Cell [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Cutaneous Involvement [NCIt concept]
- Cytoplasmic Membrane-Bound Granules Present [NCIt concept]
- Endocrine Differentiation [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Expression of Neuroendocrine Markers Present [NCIt concept]
- High Mitotic Activity [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Neuroendocrine Differentiation [NCIt concept]
- Poorly Differentiated Neuroendocrine Lesion [NCIt concept]
- Single Cell Necrosis [NCIt concept]
- Trabecular Pattern [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Dermis [NCIt concept]
- Female Reproductive System [NCIt concept]
- Genitourinary System [NCIt concept]
- Skin [NCIt concept]
- Vulva [NCIt concept]
disease_may_have_associated_disease
- Merkel Cell Polyoma Virus Infection [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Trisomy 6 [NCIt concept]
- del(1p36) [NCIt concept]

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