Preferred Label : GAIA Level 3 Major Functional Defect;
NCIt synonyms : Global Alignment of Immunization safety Assessment in pregnancy Level 3 Major Functional
Defect;
NCIt related terms : Level 3 Major Functional Defect;
NCIt definition : GAIA Level 3 Major Functional Defect is defined by two criteria: first, at least one
of the following requirements must be met: a) For live births, there must be alterations
in the functioning of one or more organs or body parts that are not due to a structural
defect, that are present at live birth (or propensity to develop alteration present
at live birth), and that persist beyond the immediate peripartum period, unless treated
through gene therapy or stem cell transplantation; OR b) For stillbirths or spontaneous
or therapeutic abortions, there must be alterations in the functioning of one or more
organs or body parts that are not due to a structural defect; second, at least one
of the following requirements must be met: a) Documented confirmation of a diagnosis
made by a clinician who has some experience diagnosing functional defects; OR b) Confirmation
of a diagnosis using either individual (ICD-9/ICD-10) codes or as part of an ICD-9/ICD-10
code based algorithm, for which the outcome (individual code or algorithm) has been
validated.;
Alternative definition : GAIA: Level 3 Major Functional Defect is defined by two criteria: first, at least
one of the following requirements must be met: a) For live births, there must be alterations
in the functioning of one or more organs or body parts that are not due to a structural
defect, that are present at live birth (or propensity to develop alteration present
at live birth), and that persist beyond the immediate peripartum period, unless treated
through gene therapy or stem cell transplantation; OR b) For stillbirths or spontaneous
or therapeutic abortions, there must be alterations in the functioning of one or more
organs or body parts that are not due to a structural defect; second, at least one
of the following requirements must be met: a) Documented confirmation of a diagnosis
made by a clinician who has some experience diagnosing functional defects; OR b) Confirmation
of a diagnosis using either individual (ICD-9/ICD-10) codes or as part of an ICD-9/ICD-10
code based algorithm, for which the outcome (individual code or algorithm) has been
validated.;
NCI Metathesaurus CUI : CL509192;
Origin ID : C127967;
UMLS CUI : C4289124;
Semantic type(s)
concept_is_in_subset