Preferred Label : GAIA Level 2 Major Functional Defect;
NCIt synonyms : Global Alignment of Immunization safety Assessment in pregnancy Level 2 Major Functional
Defect;
NCIt related terms : Level 2 Major Functional Defect;
NCIt definition : GAIA Level 2 Major Functional Defect is defined by two criteria: first, at least one
of the following requirements must be met: a) For live births, there must be alterations
in the functioning of one or more organs or body parts that are not due to a structural
defect, that are present at live birth (or propensity to develop alteration present
at live birth), and that persist beyond the immediate peripartum period, unless treated
through gene therapy or stem cell transplantation; OR b) For stillbirths or for spontaneous
or therapeutic abortions, there must be alterations in the function of one or more
organs or body parts that are not due to a structural defect; second, there must be
documented confirmation of a diagnosis made by a clinician who is experienced in diagnosing
congenital anomalies, and who has the highest level of training in the diagnosis of
functional defects for the specific setting.;
Alternative definition : GAIA: Level 2 Major Functional Defect is defined by two criteria: first, at least
one of the following requirements must be met: a) For live births, there must be alterations
in the functioning of one or more organs or body parts that are not due to a structural
defect, that are present at live birth (or propensity to develop alteration present
at live birth), and that persist beyond the immediate peripartum period, unless treated
through gene therapy or stem cell transplantation; OR b) For stillbirths or for spontaneous
or therapeutic abortions, there must be alterations in the function of one or more
organs or body parts that are not due to a structural defect; second, there must be
documented confirmation of a diagnosis made by a clinician who is experienced in diagnosing
congenital anomalies, and who has the highest level of training in the diagnosis of
functional defects for the specific setting.;
NCI Metathesaurus CUI : CL509172;
Origin ID : C127966;
UMLS CUI : C4289168;
Semantic type(s)
- concept_is_in_subset
