PRAME wt Allele

Preferred Label : PRAME wt Allele;

NCIt synonyms : CT130; OIP-4; OIP4; Preferentially Expressed Antigen in Melanoma wt Allele; MAPE;

NCIt definition : Human PRAME wild-type allele is located in the vicinity of 22q11.22 and is approximately 12 kb in length. This allele, which encodes melanoma antigen preferentially expressed in tumors protein, is involved in transcriptional repression. Aberrant expression of the gene is associated with melanoma and some acute leukemias.;

NCI Metathesaurus CUI : CL508929;

GenBank Accession Number : U65011;

Details

Origin ID

C127929;

UMLS CUI

C4284211;

Automatic exact mappings (from CISMeF team)
- Prame nuclear receptor transcriptional regulator [OMIM gene]
OMIM relation
- Prame nuclear receptor transcriptional regulator [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 22q11.22 [NCIt concept]
gene_plays_role_in_process
- Negative Regulation of Apoptosis [NCIt concept]
- Negative Regulation of Cell Differentiation [NCIt concept]
- Stimulation of Cell Proliferation [NCIt concept]
- Transcriptional Regulation [NCIt concept]
- Transcriptional Repression [NCIt concept]

Keyword's position in hierarchy(ies) :

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